3rd Workshop on Research Definitions for Reserve and Resilience in Cognitive Aging & Dementia

October 31-November 1, 2021
Bethesda, MD

 

PROGRAM

All times in US Eastern.

SUNDAY, OCTOBER 31, 2021

TIME
SESSION
CHAIR/PRESENTER
8:00-8:50
Breakfast/Meet with Senior Researchers*
9:00–9:30
Introduction - Development of Framework
Yaakov Stern, PhD, Columbia University
9:30-10:45
SESSION 1a: Application of the Framework: Non-human Studies
Co-CHAIRS:
Michela Gallagher, PhD, Johns Hopkins University

Carol Barnes, PhD, University of Arizona
9:30-9:40
Neurobiological Adaptations in Aging and Relevance for Cognitive Resilience
Jennifer Bizon, PhD, University of Florida
9:40-9:45
Q&A
9:45-9:55
Molecular Markers to Operationally Define Cognitive Reserve
Thomas Foster, PhD, University of Florida
9:55-10:00
Q&A
10:00-10:10
A Test of the Hypothesis that Factors Acting to Protect Synapse Function Will Lead to an Understanding of the Biological Basis on Cognitive Reserve
Daniel Gray, PhD, University of Arizona
10:10-10:15
Q&A
10:15-10:25
Cognitive Training to Enhance Cognitive Reserve in Aging Mice
Holly Hunsberger, PhD, Columbia University
10:25-10:30
Q&A
10:30-10:45
GROUP DISCUSSION
Chair
10:45-11:15
Coffee Break
11:15-12:30
SESSION 1b: Application of the Framework: Cohort Studies
CO-CHAIRS:
Lon White, MD, MPH, Pacific Health Research and Education Institute
William Kremen, PhD, University of California, San Diego
11:15-11:25
Cross-sectional and Longitudinal Relations between Educational Attainment and Brain Aging
Lars Nyberg, PhD, Umea University
11:25-11:30
Q&A
11:30-11:40
Reserve and Maintenance in AD; Effects on Individual Cognitive Trajectories (REMIND-ICT)
Colin Groot, PhD, VU University Medical Center Amsterdam
11:40-11:45
Q&A
11:45-11:55
Developing a Biological Marker of Cognitive Reserve with Deep Learning from Multimodal Structural MRI
Anna Marseglia, PhD, Karolinska Institute
11:55-12:00
Q&A
12:00-12:10
Aging and Memory Origins of Heterogeneity in Cognitive Trajectories Study
Eero Vuoksimaa, PhD, University of Helsinki
12:10-12:15
Q&A
12:15-12:30
GROUP DISCUSSION
Co-Chairs
12:30-13:30
Lunch
13:30-14:45
SESSION 1c: Application of the Framework: Brain Imaging
CO-CHAIRS:
Emrah Düzel, MD, German Center for Neurodegenerative Diseases
Michael Rugg, PhD, UT Dallas
13:30-13:40
Introduction
William Jagust, MD, University of California, Berkeley
13:40-13:45
Q&A
13:45-13:55
Functional Activation Patterns to Explain Cognitive Performance beyond Brain Structure and Age
Christian Habeck, PhD, Columbia University
13:55-14:00
Q&A
14:00-14:10
Improving the Moderation and Independent Effect Criteria of Cognitive Reserve
Rory Boyle, PhD, Trinity College Dublin
14:10-14:15
Q&A
14:15-14:25
Decision Tree Testing Cognition-MRI Associations to Define and Differentiate CR and BM
Lidia Vaque-Alcazar, PhD, University of Barcelona
14:25-14:30
Q&A
14:30-14:45
GROUP DISCUSSION
14:45-15:15
SESSION 1 (a, b, c): Discussion
Yaakov Stern, PhD, Columbia University
15:15-15:45
Coffee Break
15:45-17:20
SESSION 2: How Do You Share Data?/How to Access It?
CO-CHAIRS:
Kristine Beate Walhovd, PhD, University of Oslo
Dorene Rentz, PsyD, Harvard Medical School
15:45-15:50
Session Overview
Co-Chairs
15:50-16:05
New NIA Sharing Requirements
Jennie Larkin, PhD, NIA
16:05-16:20
Models of Data Sharing
Nirav Merchant, MS, University of Arizona
16:20-16:35
Sharing non-human data
Amy Dunn, PhD, Jackson Laboratory
16:35-16:50
Human Data Sharing
Scott Hofer, PhD, University of Victoria
16:50-17:20
SESSION 2: Discussion
Co-Chairs
17:20-19:00
Networking Reception

MONDAY, NOVEMBER 1, 2021

TIME
8:00-8:50
9:00-9:05
9:05-10:20
9:05-9:10
9:10–9:20
9:20-9:30
9:30-9:40
9:40-9:50
9:50-10:20
10:20-10:50
10:50–12:45
10:50–10:55
10:55–11:15
11:15–11:35
11:35–11:55
11:55–12:15
12:15 – 12:45
12:45–13:45
13:45– 14:50
14:50–15:00

MONDAY, NOVEMBER 1, 2021

SESSION
Breakfast/Meet with Senior Researchers*
Day 2 Program Overview
SESSION 3: Integration of the Framework from other Perspectives
Session Overview
Cognitive Aging Models of Reserve Require Increased Cognitive Competence with Age
Integration of the Framework from other Perspectives: Neuropathology
Framework in the Context of Resistance and Resilience Used in AD Biomarker Research
Linking the Concepts of Cognitive Reserve and Compensation
SESSION 3: GROUP DISCUSSION
Coffee Break
SESSION 4: Application of the Framework in other Areas
Session Overview
Genetics
Economics
Cognitive Intervention
Brain Stimulation
SESSION 4: GROUP DISCUSSION
Lunch
SESSION 5: OPEN DISCUSSION - Future Directions
Concluding Remarks

MONDAY, NOVEMBER 1, 2021

CHAIR/PRESENTER
Breakfast/Meet with Senior Researchers*
Yaakov Stern, PhD, Columbia University
CO-CHAIRS:
Marcus Richards, PhD, UCL
Nikolaos Scarmeas, MD, MS, Columbia University
Co-Chairs
Denise Park, PhD, University of Texas at Dallas
Thomas Montine, MD, Stanford University
Prashanthi Vemuri, PhD, Mayo Clinic
Roberto Cabeza, PhD, Duke University
Co-Chairs
Coffee Break
Co-CHAIRS:
Changiz Geula, PhD, Northwestern University
David Bartrés-Faz, PhD, University of Barcelona
Co-Chairs
Timothy Hohman, PhD, Vanderbilt University Medical Center
Robert Willis, PhD, University of Michigan
Sylvie Belleville, PhD, University of Montreal
Alvaro Pascual-Leone, PhD, Harvard Medical School
Co-Chairs
Lunch
Yaakov Stern, PhD, Chair, Columbia University
Marilyn Albert, PhD, Johns Hopkins University
Carol Barnes, PhD, University of Arizona
Roberto Cabeza, PhD, Duke University
Alvaro Pascual-Leone, MD, PhD, Harvard Medical School
Peter Rapp, PhD, National Institute on Aging
Yaakov Stern, PhD, Columbia University

*If you are participating in-person and are an early-career investigator, you have the option to be part of the Mentoring Sessions. Signal your interest to participate here.

3rd WORKSHOP VIDEO RECORDINGS

DAY 1 – AM

DAY 1 – PM

DAY 2 – AM

DAY 2 – PM

News & Stories

Review the 1st Workshop

2019

Review the 2nd Workshop

2020

Review the 4th Workshop

2024