3rd Workshop on Research Definitions for Reserve and Resilience in Cognitive Aging & Dementia
October 31-November 1, 2021
Bethesda, MD
PROGRAM
All times in US Eastern.
SUNDAY, OCTOBER 31, 2021
CHAIR/PRESENTER
8:00-8:50
Breakfast/Meet with Senior Researchers*
9:00–9:30
Introduction - Development of Framework
Yaakov Stern, PhD, Columbia University
9:30-10:45
SESSION 1a: Application of the Framework: Non-human Studies
Co-CHAIRS:
Michela Gallagher, PhD, Johns Hopkins University
Carol Barnes, PhD, University of Arizona
Michela Gallagher, PhD, Johns Hopkins University
Carol Barnes, PhD, University of Arizona
9:30-9:40
Neurobiological Adaptations in Aging and Relevance for Cognitive Resilience
Jennifer Bizon, PhD, University of Florida
9:40-9:45
Q&A
9:45-9:55
Molecular Markers to Operationally Define Cognitive Reserve
Thomas Foster, PhD, University of Florida
9:55-10:00
Q&A
10:00-10:10
A Test of the Hypothesis that Factors Acting to Protect Synapse Function Will Lead to an Understanding of the Biological Basis on Cognitive Reserve
Daniel Gray, PhD, University of Arizona
10:10-10:15
Q&A
10:15-10:25
Cognitive Training to Enhance Cognitive Reserve in Aging Mice
Holly Hunsberger, PhD, Columbia University
10:25-10:30
Q&A
10:30-10:45
GROUP DISCUSSION
Chair
10:45-11:15
Coffee Break
11:15-12:30
SESSION 1b: Application of the Framework: Cohort Studies
CO-CHAIRS:
Lon White, MD, MPH, Pacific Health Research and Education Institute
William Kremen, PhD, University of California, San Diego
Lon White, MD, MPH, Pacific Health Research and Education Institute
William Kremen, PhD, University of California, San Diego
11:15-11:25
Cross-sectional and Longitudinal Relations between Educational Attainment and Brain Aging
Lars Nyberg, PhD, Umea University
11:25-11:30
Q&A
11:30-11:40
Reserve and Maintenance in AD; Effects on Individual Cognitive Trajectories (REMIND-ICT)
Colin Groot, PhD, VU University Medical Center Amsterdam
11:40-11:45
Q&A
11:45-11:55
Developing a Biological Marker of Cognitive Reserve with Deep Learning from Multimodal Structural MRI
Anna Marseglia, PhD, Karolinska Institute
11:55-12:00
Q&A
12:00-12:10
Aging and Memory Origins of Heterogeneity in Cognitive Trajectories Study
Eero Vuoksimaa, PhD, University of Helsinki
12:10-12:15
Q&A
12:15-12:30
GROUP DISCUSSION
Co-Chairs
12:30-13:30
Lunch
13:30-14:45
SESSION 1c: Application of the Framework: Brain Imaging
CO-CHAIRS:
Emrah Düzel, MD, German Center for Neurodegenerative Diseases
Michael Rugg, PhD, UT Dallas
Emrah Düzel, MD, German Center for Neurodegenerative Diseases
Michael Rugg, PhD, UT Dallas
13:30-13:40
Introduction
William Jagust, MD, University of California, Berkeley
13:40-13:45
Q&A
13:45-13:55
Functional Activation Patterns to Explain Cognitive Performance beyond Brain Structure and Age
Christian Habeck, PhD, Columbia University
13:55-14:00
Q&A
14:00-14:10
Improving the Moderation and Independent Effect Criteria of Cognitive Reserve
Rory Boyle, PhD, Trinity College Dublin
14:10-14:15
Q&A
14:15-14:25
Decision Tree Testing Cognition-MRI Associations to Define and Differentiate CR and BM
Lidia Vaque-Alcazar, PhD, University of Barcelona
14:25-14:30
Q&A
14:30-14:45
GROUP DISCUSSION
14:45-15:15
SESSION 1 (a, b, c): Discussion
Yaakov Stern, PhD, Columbia University
15:15-15:45
Coffee Break
15:45-17:20
SESSION 2: How Do You Share Data?/How to Access It?
CO-CHAIRS:
Kristine Beate Walhovd, PhD, University of Oslo
Dorene Rentz, PsyD, Harvard Medical School
Kristine Beate Walhovd, PhD, University of Oslo
Dorene Rentz, PsyD, Harvard Medical School
15:45-15:50
Session Overview
Co-Chairs
15:50-16:05
New NIA Sharing Requirements
Jennie Larkin, PhD, NIA
16:05-16:20
Models of Data Sharing
Nirav Merchant, MS, University of Arizona
16:20-16:35
Sharing non-human data
Amy Dunn, PhD, Jackson Laboratory
16:35-16:50
Human Data Sharing
Scott Hofer, PhD, University of Victoria
16:50-17:20
SESSION 2: Discussion
Co-Chairs
17:20-19:00
Networking Reception
MONDAY, NOVEMBER 1, 2021
8:00-8:50
9:00-9:05
9:05-10:20
9:05-9:10
9:10–9:20
9:20-9:30
9:30-9:40
9:40-9:50
9:50-10:20
10:20-10:50
10:50–12:45
10:50–10:55
10:55–11:15
11:15–11:35
11:35–11:55
11:55–12:15
12:15 – 12:45
12:45–13:45
13:45– 14:50
14:50–15:00
MONDAY, NOVEMBER 1, 2021
Breakfast/Meet with Senior Researchers*
Day 2 Program Overview
SESSION 3: Integration of the Framework from other Perspectives
Session Overview
Cognitive Aging Models of Reserve Require Increased Cognitive Competence with Age
Integration of the Framework from other Perspectives: Neuropathology
Framework in the Context of Resistance and Resilience Used in AD Biomarker Research
Linking the Concepts of Cognitive Reserve and Compensation
SESSION 3: GROUP DISCUSSION
Coffee Break
SESSION 4: Application of the Framework in other Areas
Session Overview
Genetics
Economics
Cognitive Intervention
Brain Stimulation
SESSION 4: GROUP DISCUSSION
Lunch
SESSION 5: OPEN DISCUSSION - Future Directions
Concluding Remarks
MONDAY, NOVEMBER 1, 2021
CHAIR/PRESENTER
Breakfast/Meet with Senior Researchers*
Yaakov Stern, PhD, Columbia University
CO-CHAIRS:
Marcus Richards, PhD, UCL
Nikolaos Scarmeas, MD, MS, Columbia University
Marcus Richards, PhD, UCL
Nikolaos Scarmeas, MD, MS, Columbia University
Co-Chairs
Denise Park, PhD, University of Texas at Dallas
Thomas Montine, MD, Stanford University
Prashanthi Vemuri, PhD, Mayo Clinic
Roberto Cabeza, PhD, Duke University
Co-Chairs
Coffee Break
Co-CHAIRS:
Changiz Geula, PhD, Northwestern University
David Bartrés-Faz, PhD, University of Barcelona
Changiz Geula, PhD, Northwestern University
David Bartrés-Faz, PhD, University of Barcelona
Co-Chairs
Timothy Hohman, PhD, Vanderbilt University Medical Center
Robert Willis, PhD, University of Michigan
Sylvie Belleville, PhD, University of Montreal
Alvaro Pascual-Leone, PhD, Harvard Medical School
Co-Chairs
Lunch
Yaakov Stern, PhD, Chair, Columbia University
Marilyn Albert, PhD, Johns Hopkins University
Carol Barnes, PhD, University of Arizona
Roberto Cabeza, PhD, Duke University
Alvaro Pascual-Leone, MD, PhD, Harvard Medical School
Peter Rapp, PhD, National Institute on Aging
Marilyn Albert, PhD, Johns Hopkins University
Carol Barnes, PhD, University of Arizona
Roberto Cabeza, PhD, Duke University
Alvaro Pascual-Leone, MD, PhD, Harvard Medical School
Peter Rapp, PhD, National Institute on Aging
Yaakov Stern, PhD, Columbia University
*If you are participating in-person and are an early-career investigator, you have the option to be part of the Mentoring Sessions. Signal your interest to participate here.
3rd WORKSHOP VIDEO RECORDINGS
DAY 1 – AM
DAY 1 – PM
DAY 2 – AM
DAY 2 – PM
GALLERY
